MPox
The World Health Organization (WHO) has declared mpox in the Democratic Republic of Congo (DRC) and neighboring countries to be a Public Health Emergency of International Concern (PHEIC) under the 2005 International Health Regulations (IHR) — the WHO’s highest-level alert.
This open knowledge-sharing community is in place to support research teams and encourage local research to address the pressing gaps in evidence. New data is needed to understand transmission, severity of disease, and longevity, to support vaccine development and testing, better detection, and diagnosis. Social science also strongly needs to support public health education, awareness, and detection to improve access to care and slow transmission.
In this area, you will find the latest updates/resources to support your research from across the network as well as trusted sources of further information from WHO and other organisations. Please check back here regularly as more resources and tools are added.
Mpox Literature Screening and Data Extraction Mpox outbreak mapping
French translation_WHO Mpox transmission protocol WHO Mpox Introductory Short Course
French translation_WHO Mpox transmission protocol WHO Mpox Webinar Resources
Interim guidance on social and behavioural research for the mpox public health response
This interim guidance aims to clarify standards for high-quality, ethical, social and behavioural research to strengthen the public health response to the ongoing mpox PHEIC for community protection. The guidance is particularly relevant to rapid research that aims to inform near- to real-time decision-making and action but is equally applicable to longer-term research that may be critical for informing future outbreak preparedness and response.
Download the guidance document [pdf 3.9mb]
Mpox Testing Strategy, November 2024
This testing strategy for mpox is a guide for stakeholders supporting the mpox response including Ministries of Health and other Government agencies, national mpox response task-forces, funding and implementing agencies, public health experts, epidemiologists, front-line healthcare service providers including clinicians, nurses, laboratory professionals, community healthcare workers and others involved in outbreak preparedness and response activities for enhanced community protection.
Download the strategy [pdf 3.33mb]
Latest Research Updates
News coverage on the Mpox outbreak
Mpox clade Ib and clade IIb outbreak: epidemiological overview 5 June 2025
Current data regarding mpox clade Ib and clade IIb cases within the United Kingdom. Earlier reports spanning the period from June 2022 through January 2025 contain details exclusively on clade IIb cases.
WHO Director-General declares mpox outbreak a public health emergency of international concern 14 August 2024
WHO Director-General Dr Tedros Adhanom Ghebreyesus has determined that the upsurge of mpox in the Democratic Republic of the Congo (DRC) and a growing number of countries in Africa constitutes a public health emergency of international concern (PHEIC) under the International Health Regulations (2005) (IHR).
New mpox strain mutating faster than expected, and other top health stories 30 August 2024 - World Economic Forum
The new mpox strain spreading from the Democratic Republic of Congo (DRC) is mutating faster than expected, particularly in regions lacking the resources for proper tracking, scientists report. This has led to "numerous unknowns" about the virus’s severity and transmission, complicating the global response, experts in Africa, Europe and the United States told Reuters.
Another worldwide alert – mpox is spreading. Here are three steps we can take to head it off 30 August 2024 - The Guardian
Just a little over a year since declaring that Covid-19 was no longer a public health emergency of international concern and that the 2022-23 mpox crisis had subsided, the World Health Organization finds itself warning of another crisis as cases of yet another new strain of the mpox virus spread from the Democratic Republic of the Congo to other countries in Africa and beyond.
WHO urges rapid access to mpox diagnostic tests, invites manufacturers to emergency review 29 August 2024 - World Health Organization
WHO has asked manufacturers of mpox in vitro diagnostics (IVDs) to submit an expression of interest for Emergency Use Listing (EUL). WHO has been in ongoing discussions with manufacturers about the need for effective diagnostics, particularly in low-income settings. The request for EUL expressions of interest by manufacturers is the latest development in these discussions.
↓ Regional MPox Information Overview
↓ CLINICAL RESEARCH SOURCES
↓ Mpox Outbreak Resources and Reports
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Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.1 - September 23, 2022
Access Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.1 - September 23, 2022
Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.5 November 18, 2022
Access Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.5 November 18, 2022
Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.2 of October 7, 2022
Access Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.2 of October 7, 2022
Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.7. March 3, 2023
Access Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.7. March 3, 2023
Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.3 of October 21, 2022
Access Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas. N.3 of October 21, 2022
June 17, 2022. Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas
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Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - July 8, 2022
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Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - July 1, 2022
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Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - June 24, 2022
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Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - September 9, 2022
Access Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - September 9, 2022
Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - September 2, 2022
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Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - July 29, 2022
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Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas July 22, 2022
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Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - July 15, 2022
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External Situation Report 2 - July 25, 2022
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External Situation Report 3 - July 27, 2022
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External Situation Report 4 - July 28, 2022
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External Situation Report 5 - August 1, 2022
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External Situation Report 6 - August 4, 2022
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External Situation Report 7 - August 10, 2022
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External Situation Report 8 - August 19, 2022
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External Situation Report 9 - September 2, 2022
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↓ WHO and CDC Mpox Guidelines and Advice
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Mpox (Monkeypox) Strategic Preparedness, Readiness, and Response Plan (SPRP)
Access Mpox (Monkeypox) Strategic Preparedness, Readiness, and Response Plan (SPRP)
Risk communication and community engagement readiness and response toolkit: mpox
Access Risk communication and community engagement readiness and response toolkit: mpox
Surveillance, case investigation and contact tracing for mpox (monkeypox): Interim guidance, 20 March 2024
Access Surveillance, case investigation and contact tracing for mpox (monkeypox): Interim guidance, 20 March 2024
Mpox (monkeypox) FAQ
Access Mpox (monkeypox) FAQ
Public advice on recovering from mpox (monkeypox) at home
Access Public advice on recovering from mpox (monkeypox) at home
Public health advice on protecting yourself and others from mpox (monkeypox)
Access Public health advice on protecting yourself and others from mpox (monkeypox)
Public advice for men who have sex with men on preventing mpox (monkeypox)
Access Public advice for men who have sex with men on preventing mpox (monkeypox)
Mpox (monkeypox) response in Europe
Access Mpox (monkeypox) response in Europe
Diagnostic testing for the Mpox (monkeypox) virus (MPXV): interim guidance, 9 November 2023
Access Diagnostic testing for the Mpox virus (MPXV): interim guidance, 9 November 2023
Clinical characterization of mpox including monitoring the use of therapeutic interventions: statistical analysis plan, 13 October 2023
Access Clinical characterization of mpox including monitoring the use of therapeutic interventions: statistical analysis plan, 13 October 2023
Clinical management and infection prevention and control for Mpox: Interim rapid response guidance, 10 June 2022
Access Clinical management and infection prevention and control for Mpox: Interim rapid response guidance, 10 June 2022
Interim Guidance: Infection Prevention and Control for the Management of Mpox in People in Situations of Vulnerability such as Prisons and Other Custodial Facilities. 1 December 2022
Access Interim Guidance: Infection Prevention and Control for the Management of Mpox in People in Situations of Vulnerability such as Prisons and Other Custodial Facilities. 1 December 2022
Surveillance, case investigation and contact tracing for Mpox: interim guidance, 25 August 2022
Access Surveillance, case investigation and contact tracing for mpox: interim guidance, 25 August 2022
Recommendations for ethical monkeypox (Mpox) surveillance
Access Recommendations for ethical Mpox (monkeypox) surveillance
Guidance on the use of Mpox (monkeypox) vaccines. Corrected edition
Access Guidance on the use of Mpox (monkeypox) vaccines. Corrected edition
Recommendations for ethical Mpox (monkeypox) surveillance
Access Recommendations for ethical Mpox (monkeypox) surveillance
Guidance on the use of Mpox (monkeypox) vaccines
Access Guidance on the use of Mpox (monkeypox) vaccines
Mpox (monkeypox) Fact Sheet Resources from the Maryland Department of Health (MDH)
Access Mpox (monkeypox) Fact Sheet Resources from the Maryland Department of Health (MDH)
Mpox Resources for Health Professionals
Access Mpox Resources for Health Professionals
What to Do If You Are Sick
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Mpox Monitoring and Risk Assessment for Persons Exposed in the Community
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Preventing Mpox Spread to Others
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Schools & Child Care FAQ for Mpox
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↓ PAHO Mpox Documents and Reports
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Lessons from HIV in MPOX outbreak control
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Monkeypox Epidemiological Update in non-endemic countries - June 13, 2022
Access Monkeypox Epidemiological Update in non-endemic countries - June 13, 2022
VIII Ad Hoc Meeting of the PAHO Technical Advisory Group (TAG) on Vaccine Preventable Diseases. Technical report on the monkeypox outbreak in several countries, May 31, 2022 (virtual)
Access VIII Ad Hoc Meeting of the PAHO Technical Advisory Group (TAG) on Vaccine Preventable Diseases. Technical report on the monkeypox outbreak in several countries, May 31, 2022 (virtual)
Laboratory guidelines for the detection and diagnosis of monkeypox virus infection
Access Laboratory guidelines for the detection and diagnosis of monkeypox virus infection
Monkeypox in the Region of the Americas - Risk Assessment
Access Monkeypox in the Region of the Americas - Risk Assessment
IX Ad Hoc Meeting of the Technical Advisory Group (GTA) IX Ad Hoc Meeting of the PAHO Technical Advisory Group (TAG) on Vaccine Preventable Diseases, July 25, 2022 (virtual)
Access IX Ad Hoc Meeting of the Technical Advisory Group (GTA) IX Ad Hoc Meeting of the PAHO Technical Advisory Group (TAG) on Vaccine Preventable Diseases, July 25, 2022 (virtual)
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↓ Mpox Resources and Tools
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Link
Monkeypox: Social Media Postcards
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What to Do If You Are Sick
Access What to Do If You Are Sick
Mpox Monitoring and Risk Assessment for Persons Exposed in the Community
Access Mpox Monitoring and Risk Assessment for Persons Exposed in the Community
Preventing Mpox Spread to Others
Access Preventing Mpox Spread to Others
Schools & Child Care FAQ for Mpox
Access Schools & Child Care FAQ for Mpox
Triptych - Monkeypox
Access Triptych - Monkeypox
Epidemiological Update Monkeypox in women - August 26, 2022
Access Epidemiological Update Monkeypox in women - August 26, 2022
Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - August 26, 2022
Access Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - August 26, 2022
Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - August 19, 2022
Access Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - August 19, 2022
Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - August 12, 2022
Access Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - August 12, 2022
Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - August 5, 2022
Access Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - August 5, 2022
Risk communication tools on Mpox and mass events
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↓ WHO and PAHO Additional Mpox Reports
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Epidemiological Update on Monkeypox - July 9, 2022
Access Epidemiological Update on Monkeypox - July 9, 2022
Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas - July 8, 2022
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June 17, 2022. Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas
Access June 17, 2022. Weekly Situation Report on the Response to the Monkeypox Outbreak in several countries - Region of the Americas
Monkeypox Epidemiological Update in non-endemic countries - June 13, 2022
Access Monkeypox Epidemiological Update in non-endemic countries - June 13, 2022
Monkeypox Situation in the region
Access Monkeypox Situation in the region
MPOX TEMPORARY RECOMMENDATIONS UPDATE
Access MPOX TEMPORARY RECOMMENDATIONS UPDATE
PAHO: Recommendations for ethical surveillance of monkeypox
Access PAHO: Recommendations for ethical surveillance of monkeypox
IX Ad Hoc Meeting of the Technical Advisory Group (GTA) IX Ad Hoc Meeting of the PAHO Technical Advisory Group (TAG) on Vaccine Preventable Diseases, July 25, 2022 (virtual)
Access IX Ad Hoc Meeting of the Technical Advisory Group (GTA) IX Ad Hoc Meeting of the PAHO Technical Advisory Group (TAG) on Vaccine Preventable Diseases, July 25, 2022 (virtual)
The silence that harms: How to talk about Mpox without doing harm
Access The silence that harms: How to talk about Mpox without doing harm
Ethical involvement of civil society and other obligations with the population
Access Ethical involvement of civil society and other obligations with the population
Situation Report on the Response to the Mpox Outbreak in several countries - Region of the Americas. N.7. March 3, 2023
Access Situation Report on the Response to the Mpox Outbreak in several countries - Region of the Americas. N.7. March 3, 2023
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↓ Mpox Free Short Courses